Scientists At Massachusetts General Hospital Target Osteosarcoma Gene Therapy

Scientists discuss in ‘Insulin-like growth factor-I receptor tyrosine kinase inhibitor cyclolignan picropodophyllin inhibits proliferation and induces apoptosis in multidrug resistant osteosarcoma cell lines’ new findings in osteosarcoma. According to a study from the United States, Insulin-like growth factor-I receptor (IGF-IR) is an important mediator of tumor cell survival and shows prognostic significance in sarcoma.